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Topic Collections

Pathophysiology and Treatment of Hirschsprung Disease

Hirschsprung disease (HSCR) is a congenital disorder characterized by the absence of ganglion cells in the distal intestine, resulting in life-threatening functional bowel obstruction. This topic collection, focusing on Hirschsprung disease, will cover a breadth of topics, including its genetic and embryologic origin, diagnosis and treatment, long-term outcomes, and innovations on the horizon. Please find full details here. Submissions: Open until 31 July 2024

Congenital Diaphragmatic Hernia

Congenital diaphragmatic hernia (CDH) is a serious congenital birth defect disease. In the past, due to limited understanding of CDH and immature treatment methods, the mortality rate of CDH was more than 30%, and even exceeded 70% in severe cases. In recent years, significant progress has been made in prenatal diagnostic techniques, prenatal and perinatal treatment, perinatal care, intensive care, and surgical procedures, which have greatly improved the success rate of treatment for CDH patients. This topic collection highlights cutting-edge findings related to the current status of diagnosis and treatment of CDH. Read the collection here.

Pediatric Orthopedics

Pediatric orthopedic diseases are common in children from infancy to adulthood. While many high-quality studies have been published over the past few decades, there is much to be learned regarding the correct diagnosis and treatment in children with pediatric orthopedic diseases. This topic collection aims to publish all information relevant to the clinical practice, operative techniques and laboratory and imaging tests of pediatric traumatic injuries, skeletal deformities, tumors, sports medicine and other common orthopedic diseases. Read the collection here.

Neonatal Surgery

Congenital malformations and inflammatory infections are common causes of pediatric surgical diseases. Many diseases require surgical intervention in the neonatal period. Observational and experimental studies have established novel therapy strategies, mechanisms and treatments in neonates, which improved the development of neonatal surgery. This topic collection aims to publish cutting-edge findings in the fields of Necrotizing enterocolitis (NEC), Biliary atresia (BA), Esophageal Atresia (EA), Congenital choledochal cyst, Omphalocele and Minimally Invasive Surgery/Robotic Surgery. Read the collection here.