Case report: neurological complications associated with epidural analgesia in children: a report of 4 cases of ambiguous etiologies

Anesth Analg. 2012 Dec;115(6):1365-70. doi: 10.1213/ANE.0b013e31826918b6. Epub 2012 Nov 9.

Abstract

The safety and utility of pediatric epidural analgesia is well established, but the risk of permanent neurological injury is unknown and largely must be extrapolated from adult literature. In this article we present a series of 4 cases of longterm or permanent neurologic complications associated with epidural analgesia. Possible mechanisms of injury and implications for practice are discussed.

Publication types

  • Case Reports

MeSH terms

  • Analgesia, Epidural / adverse effects*
  • Anesthesia, General
  • Anesthetics, Local / administration & dosage
  • Anesthetics, Local / therapeutic use
  • Bupivacaine / administration & dosage
  • Bupivacaine / therapeutic use
  • Child
  • Colitis, Ulcerative / surgery
  • Complex Regional Pain Syndromes / complications
  • Complex Regional Pain Syndromes / therapy
  • Dexamethasone / therapeutic use
  • Female
  • Funnel Chest / surgery
  • Humans
  • Infant
  • Laminectomy
  • Magnetic Resonance Imaging
  • Male
  • Nervous System Diseases / drug therapy
  • Nervous System Diseases / etiology*
  • Nervous System Diseases / surgery
  • Pain, Postoperative / drug therapy
  • Paralysis / chemically induced
  • Postoperative Complications / drug therapy
  • Postoperative Complications / etiology*
  • Postoperative Complications / surgery
  • Recovery of Function
  • Spinal Cord Compression / complications
  • Spine / pathology
  • Urogenital Abnormalities / surgery

Substances

  • Anesthetics, Local
  • Dexamethasone
  • Bupivacaine