Congenital lung lesions

Clin Perinatol. 2012 Jun;39(2):331-47. doi: 10.1016/j.clp.2012.04.009.

Abstract

Confusion, controversy, and uncertainty are all terms applicable to the diagnosis and management of congenital lung lesions both prenatally and postnatally. This review examines the current status of fetal diagnosis and treatment of these lesions; reviews the various classifications, including congenital cystic adenomatoid malformation/congenital pulmonary airway malformation, sequestrations, variants and hybrid lesions; discusses the risk of malignant transformation or misdiagnosis with pleuropulmonary blastoma; presents the arguments in favor and against resection of asymptomatic lesions, the timing of such resection, and the long-term pulmonary function after resection; and reviews the experience with thoracoscopic resection of congenital lung lesions.

Publication types

  • Review

MeSH terms

  • Betamethasone / therapeutic use*
  • Bronchopulmonary Sequestration / diagnostic imaging
  • Bronchopulmonary Sequestration / surgery
  • Cystic Adenomatoid Malformation of Lung, Congenital / diagnosis*
  • Cystic Adenomatoid Malformation of Lung, Congenital / diagnostic imaging
  • Cystic Adenomatoid Malformation of Lung, Congenital / surgery
  • Diagnosis, Differential
  • Female
  • Humans
  • Hydrops Fetalis / diagnosis*
  • Hydrops Fetalis / drug therapy
  • Hydrops Fetalis / prevention & control
  • Lung Neoplasms / congenital*
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / therapy
  • Pregnancy
  • Prenatal Diagnosis*
  • Pulmonary Atresia / diagnosis
  • Pulmonary Blastoma / congenital*
  • Pulmonary Blastoma / diagnosis
  • Pulmonary Blastoma / therapy
  • Ultrasonography

Substances

  • Betamethasone

Supplementary concepts

  • Pleuropulmonary blastoma