Downsizing to resectability of a large solid and cystic papillary tumor of the pancreas by single-agent chemotherapy

J Pediatr Surg. 2009 Oct;44(10):e23-5. doi: 10.1016/j.jpedsurg.2009.07.026.

Abstract

Solid and cystic pseudopapillary tumor (SCPT) is an uncommon cancer that typically affects young women. Most patients with SCPT have a favorable prognosis provided a complete resection is attained. There are anecdotal reports of the use of neoadjuvant chemotherapy or radiation therapy for patients with unresectable tumors. We report the case of a 14-year-old female with SCPT who was successfully downsized with gemcitabine before definitive surgical resection.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antimetabolites, Antineoplastic / pharmacology
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Biopsy / methods
  • Carcinoma, Papillary / drug therapy
  • Carcinoma, Papillary / pathology*
  • Carcinoma, Papillary / surgery*
  • Cystadenoma, Papillary / drug therapy
  • Cystadenoma, Papillary / pathology*
  • Cystadenoma, Papillary / surgery*
  • Deoxycytidine / analogs & derivatives*
  • Deoxycytidine / pharmacology
  • Deoxycytidine / therapeutic use
  • Female
  • Gemcitabine
  • Humans
  • Neoadjuvant Therapy / methods*
  • Pancreas / drug effects*
  • Pancreas / pathology*
  • Pancreatectomy
  • Pancreatic Neoplasms / drug therapy
  • Pancreatic Neoplasms / pathology*
  • Pancreatic Neoplasms / surgery*
  • Treatment Outcome

Substances

  • Antimetabolites, Antineoplastic
  • Deoxycytidine
  • Gemcitabine