Analysis of three factors’ influence on response measures
| TVR>65 n (%) | TVR<65 n (%) | P value | Nec>50 n (%) | Nec<50 n (%) | P value | Reduced IDRF n (%) | No reduced IDRF n (%) | P value | Complication Yes n (%) | Complication No n (%) | P value | |
| Pretreatment MYCN testing | ||||||||||||
| Yes | 22 (62.9) | 13 (37.1) | 0.79 | 25 (71.4) | 10 (28.6) | 0.39 | 16 (45.7) | 19 (54.3) | 0.12 | 14 (40) | 21 (60) | 0.61 |
| No | 18 (66.7) | 9 (33.3) | 22 (81.5) | 5 (18.5) | 7 (25.9) | 20 (74.1) | 13 (48.1) | 14 (51.9) | ||||
| Metastases | ||||||||||||
| Yes | 30 (62.5) | 18 (37.5) | 0.35 | 34 (70.8) | 14 (29.2) | 0.16 | 16 (33.3) | 32 (66.7) | 0.35 | 16 (33.3) | 32 (66.7) | 0.005* |
| No | 11 (78.6) | 3 (21.4) | 13 (92.9) | 1 (7.1) | 7 (50) | 7 (50) | 11 (78.6) | 3 (21.4) | ||||
| Age at diagnosis (y) | ||||||||||||
| <1.5 | 14 (82.4) | 3 (17.6) | 0.14 | 16 (94.1) | 1 (5.9) | 0.049* | 8 (47.1) | 9 (52.9) | 0.4 | 10 (58.8) | 7 (41.2) | 0.16 |
| >1.5 | 27 (60) | 18 (40) | 31 (68.9) | 14 (31.1) | 16 (34.8) | 30 (65.2) | 17 (37.8) | 28 (62.2) |
*Denotes statistical significance if p<0.05.
IDRF, image-defined risk factor; TVR, tumor volume reduction.