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Predictive factors for time to full enteral feeding after pyloromyotomy for infantile hypertrophic pyloric stenosis
  1. David Eriksson1 and
  2. Martin Salö1,2
  1. 1Department of Clinical Sciences, Pediatrics, Lund University, Lund, Sweden
  2. 2Department of Pediatric Surgery, Skåne University Hospital, Lund, Sweden
  1. Correspondence to Dr Martin Salö; martin.salo{at}


Background The aim of the study was to evaluate how different parameters in the preoperative, perioperative, and postoperative period affect time to full enteral feeding (TFEF) in children undergoing pyloromyotomy.

Methods A retrospective study of all children operated for infantile hypertrophic pyloric stenosis between 2001 and 2017 was conducted. Parameters in demographics and in the preoperative and postoperative period were evaluated against TFEF (hours) using linear regression models.

Results In the whole cohort of 175 children, mean TFEF was 47 hours with Standard Deviation (SD) of ±35. In the multivariate model, TFEF decreased with age [beta (B): −0.62; 95% confidence interval (95% CI) −1.05 to −0.19; p=0.005) and increased with the presence of severe underlying disease (congenital heart defect or syndrome) (B: 26.5; 95% CI 3.3 to 49.7; p=0.026). Hence, for every day of age, the time to fully fed decreased by 0.6 hour, and the presence of an underlying disease increased the time to fully fed with over one day. TFEF did not seem to be affected by prematurity, weight loss, symptom duration, preoperative acid/base balance or electrolyte values, surgical method, or method of postoperative feeding.

Conclusions TFEF decreased with higher age and increased in children with a severe underlying disease. These results may be useful in providing adequate parental information regarding what affects TFEF and the length of hospital stay.

  • pediatric surgery

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  • Contributors DE collected the data, drafted the initial manuscript and helped revise the final manuscript. MS conceptualized the design, gathered the cohort, performed the statistical analyses and revised the manuscript. Both authors approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Ethical approval This study has been approved by the Regional Ethical Review Board (DNR number 2010/49) and by the regional hospital ethics committee and was done in accordance with the principles outlined in the Declaration of Helsinki.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement Data are available upon reasonable request. Data are available upon request to the author ( The data are in form of deidentified participant data.

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